Promotes
Cardiovascular and Neurological Health*
Supports Metabolic Health*
Purified to eliminate mercury
PRODUCT ALSO KNOWN AS
Eicosapentaenoic acid (EPA), Docosahexaenoic acid (DHA)
PRODUCT DISCUSSION
PhysioLogics' EPA 180 mg / DHA 120 mg softgels deliver cholesterol-free fish
oil, which contains the longchain polyunsaturated Omega-3 fatty acids. Each
softgel provides 18% Eicosapentaenoic acid (EPA) and 12% Docosahexaenoic acid (DHA).
STRUCTURE AND FUNCTION
The family of Omega-3 fatty acids form part of the structure of membranes of
every cell in the body and are essential for normal cell growth. EPA and DHA are
direct precursors of a wide range of biologically important lipid mediators used
in the support of virtually all biological functions, including those of the
cardiovascular, reproductive, immune, and nervous systems.* EPA is beneficial
for circulation and makes more efficient use of myocardial oxygen for heart
health maintenance. As an Omega-3 fatty acid, EPA supports a healthy vascular
system.*
DHA is the most prevalent fatty acid of rod photoreceptor disc membranes and synaptic terminals, and is necessary for proper excitable membrane functions and fluidity. In addition, higher concentrations of DHA are correlated with healthy C-reactive protein levels in granulocytes, promoting healthy effects of these cells on tissue.*
INDICATIONS
While the human body can enzymatically elongate and desaturate the parent
Omega-3 a-Linolenic Acid into EPA and, to a lesser extent, DHA, this process may
be limited. American diets may not include ample amounts of fish, a rich source
of Omega-3s. PhysioLogics' EPA 180 mg / DHA 120 mg provides a dietary supplement
for individuals who want to receive a daily supply of Omega-3 fatty acids.*
HOW CLIENTS MAY BENEFIT
- Provides essential components of cell membranes for normal cell growth*
- Supports circulation for heart health*
- Promotes cerebral and central nervous system health and maintenance*
CLINICAL EVIDENCE
- The Physician's Health Study followed apparently healthy men for up to 17 years. Analysis of the blood indicated that higher levels of Omega-3 fatty acids were found in those with a healthier cardiovascular system and quality of life.
- Researchers at the Harvard School of Public Health followed over 5,100 women for up to 16 years and found that diets with a higher consumption of Omega-3 fatty acids were associated with heart health maintenance and quality of life.
- A study assessing the cognitive abilities of over 200 men and women aged 63-74 over a four year period showed higher level of Omega-3 fatty acids in erythrocyte membranes obtained from normal diet were associated with maintenance of cognitive function in the elderly.
SUMMARY
Omega-3 polyunsaturated fatty acids are nutrients that may be lacking in most
American diets. Consumption of Omega-3 fatty acids may reduce the risk of
coronary heart disease. FDA evaluated the data and determined that, although
there is scientific evidence supporting the claim, the evidence is not
conclusive. Supplementing your clients' nutrition with PhysioLogics' EPA 180 mg
/ DHA 120 mg will support their cardiovascular, nervous, and circulatory
systems, as well as overall health.*
SUGGESTED DOSAGE
For adults, take one (1) softgel three times a day, preferably with a meal, or
follow the advice of your health care professional. As a reminder, discuss the
supplements and medications you take with your health care providers.
REFERENCES
Albert CM, Campos H, Stampfer MJ, Ridker PM, Manson JE, Willet WC, Ma J. Blood
levels of long-chain n-3 fatty acids and the risk of sudden death. N Engl J
Med. 2002. 346(15):1113-8.
Bjerve, K. w3 fatty acid deficiency in man: Implications for the requirement of alpha-linolenic acid and longchain w3 fatty acids. World Rev Nutr Diet. 1991;66:133-42.
Carroll D, Roth M. Evidence for the cardioprotective effects of Omega-3 fatty acids. Ann Pharmacther.2002. 36(12):1950-6.
DeLuca P, Rothman D, Zurier R. Marine and botanical lipids as immunomodulatory and therapeutic agents in the treatment of rheumatoid arthritis. Rheumatic disease clinics of North America. 1995. 21(3):759-77
Heude, B., Ducimetiere, P., and Berr, C. Cognitive decline and fatty acid composition of erythrocyte membranes- The EVA study. Am J of Clin Nutr. 2003 77(4):803-8.
Hu F, Cho E, Rexrode K, Albert C, Manson J. Fish and long-chain w-3 fatty acid intake and risk of coronary heart disease and total mortality in diabetic women. Circulation. 2003. 107:1852-7
Sanders TA. Dietary fat and postprandial lipids. Curr Atheroscler Rep. 2003. 5(6):445-51.
Simopoulos A. Symposium: Role of poultry products in enriching the human diet with N-3 PUFA. Human requirement for the N-3 polyunsaturated fatty acids. Poult Sci. 2000. 79(7):961-70
Youdim K, Martin A, Joseph J. Essential fatty acids and the brain: possible health implications. Int J Devl Neuroscience. 2000. 18:383-99
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