Amino
Acid Supplementation
Supports Cardiac Muscle Function*
PRODUCT ALSO KNOWN AS
b-amino ethane sulfonic acid
PRODUCT DISCUSSION
L-Taurine is an amino acid-like compound and a component of bile acids. L-Taurine
is one of the most abundant free amino acids in the heart, brain and muscle,
and is involved in a broad spectrum of metabolic processes.*
STRUCTURE AND FUNCTION
Taurine was first isolated in 1827 from ox bile (Bos taurus) and thus named
accordingly. Initially considered to be an inert end-product of sulfur amino
acid metabolism, evidence now exists that Taurine plays a role in a broad
spectrum of physiological functions, including cell membrane stabilization,
nervous system development, modulation of neuronal excitability,
osmoregulation, and glycolysis and glycogenesis. Because of reports describing
certain deficiencies, Taurine is characterized as a conditionally essential
nutrient.*
Taurine is synthesized in the liver from Methionine, an essential amino acid, and Cysteine, a non-essential amino acid. Not considered a true amino acid, Taurine contains a sulfonic acid group in place of the carboxylic group of what would normally be Alanine. Because of this feature, Taurine cannot be incorporated into proteins and therefore exists as a free amino acid in most animal tissues and biological fluids. It is the most abundant free amino acid in cardiac and skeletal muscle, platelets and the developing central nervous system, and exists as the second most abundant free amino acid in the brain.*
While the full mechanisms of action of Taurine are not completely understood, its varied biological activity and virtually ubiquitous presence indicate a prominent role in biological function. In heart muscle, Taurine promotes free Calcium levels to support the heart beat when Calcium is limiting, yet also supports healthy levels when Calcium is abundant. This is not accomplished through Calcium ion chelation, rather via modification of cardiac high-affinity Calcium binding sites. This ionotropic effect serves to support the normal function of the heart.*
INDICATIONS
Taurine is a conditionally essential nutrient important for the heart.
Supplementing your clients' diets with Taurine may be an opportune way to
replenish plasma Taurine levels and receive a daily supply of this important
nutrient to promote heart health in addition to a variety of other metabolic
processes.*
HOW CLIENTS MAY BENEFIT
- Receive a conditionally essential nutrient important for heart health.*
- L-Taurine plays a role in the metabolic processes in the muscle.*
- Taurine plays a role in the control of ionic flux, thereby effecting metabolic processes.*
- Supports cardiac and skeletal muscle function.*
SUMMARY
L-Taurine is a conditionally essential nutrient that plays a vital role in
heart health. As one of the most abundant free amino acids in several human
tissues, L-Taurine plays a key role in several biological processes, including
ionic flux to support cardiovascular function.*
SUGGESTED DOSAGE
For adults, take one (1) tablet twice daily, preferably with a meal or follow
the advice of your health care professional. As a reminder, discuss the
supplements and medications you take with your health care providers.
REFERENCES
Hayes, K.C., et al. Taurine. Modern Nutr in Health and Disease. 8th ed. Vol.
1.Lea & Febiger. Philadelphia, PA. 1994. 477-485.
Huxtable, R.J. Taurine in the central nervous system and the mammalian actions of taurine. Progress in Neuro. 1989. 32 (6): 471-533.
Kendler, B.S. Taurine: an overview of its role in preventative medicine. Prev Med. 1989. 18; 79-100.
Sole, M., et al. Conditional nutritional requirements: therapeutic relevance to heart failure. Herz. 2002. 27(2); Mar: 174-8.
Wright, C.E., et al. Taurine: biological update. Ann Rev Biochem. 1986. 55: 427-53.
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