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Quick Overview
Real Krill Enhanced with DHA & EPA 60S/G Science-based nutrition Dietary supplement High-potency source of omega-3 DHA and EPA* Supports healthy brain, joint, and other organ functions* Promotes cardiovascular health* In this product, the superior bioactivity of krill ome
Real Krill Enhanced with DHA & EPA 60S/G
- Science-based nutrition
- Dietary supplement
- High-potency source of omega-3 DHA and EPA*
- Supports healthy brain, joint, and other organ functions*
- Promotes cardiovascular health*
In this product, the superior bioactivity of
krill omega-3 DHA and EPA as phospholipids is augmented by DHA and EPA from
fish. These vital lipids are building blocks of the cell membrane systems
that manage most of the important life functions. Real Krill Enhanced with
DHA & EPA ensures a generous daily supply of DHA, together with EPA for
effective support of health and well-being.
Suggested Use: For omega-3 maintenance, take 2 softgels per day
after a meal. For added cardiovascular protection, take 3 - 4 softgel
capsules per day. Higher intakes may be beneficial, under a physician’s
care.
Supplement Facts
Serving Size: 2 capsules
Serving per container: 30 servings
Amount Per Serving        ÂÂ
%DV
Authentic Krill Oil plus Fish Oil Omega-3 Complex, providing:
--------------------------------------------------------------------------------------------
Phospholipids, minimum (min.) 240 mg â€Â
--------------------------------------------------------------------------------------------
Omega-3 Fatty Acids, min. 800 mg â€Â
DHA (DocosaHexaenoic Acid), min. 512 mg â€Â
EPA (EicosaPentaenoic Acid), min. 134 mg â€Â
--------------------------------------------------------------------------------------------
Astaxanthin, min. 30 mcg â€Â
--------------------------------------------------------------------------------------------
†Daily Value not established.
Other Ingredients: Softgel capsule (gelatin, glycerin,
purified water), vanillin.
Contains nothing other than listed ingredients.
Not Suitable for Vegetarians
60S/G
Real Krill is a 100 percent authentic dietary
supplement, a lipid nutrient complex sustainably harvested from the Antarctic
Krill, Euphausia superba. Krill are shrimp-like ocean creatures (Crustaceans)
that feed exclusively on algae, the primary producers in the marine food
chain. Antarctic krill are so abundant they could be the largest single
species mass on the planet.1
Krill thrive in the frigid Antarctic seas due to their ample content of the
long-chain omega-3 fatty acids DHA (DocosaHexaenoic Acid) and EPA (EicosaPentaenoic
Acid). By remaining fluid at temperatures way below freezing, these vital
lipid nutrients assist krill to routinely survive, feed and reproduce.
Krill Oil’s Vital Lipids Offer A Range of Benefits
Krill oil is sometimes compared to fish oil as
an omega-3 dietary supplement. But authentic krill oil complex contains a
greater range of nutrients, and its benefits far exceed those of fish oils.
Most of the DHA and EPA of krill oil occurs linked into larger phospholipid
molecules (pronounced (fos-fo-lip-ids).2 These are preformed
building blocks for the cell membranes that drive life processes. In fish oil,
by contrast, all the DHA and EPA occurs as triglycerides, which are storage
forms of fatty acids (“fatâ€ï†). The DHA and EPA has to be removed from the
triglycerides, then linked into phospholipids prior to inserting them into
cell membranes.
Krill oil gets its red color from astaxanthin, a carotenoid nutrient.
Astaxanthin is a potent membrane antioxidant and helps ensure krill oil’s
exceptional shelf life stability.3 Fish oils lack astaxanthin and
are vulnerable to premature rancidityâ€â€oxidative degradation of the fragile
DHA and EPA molecules. Krill’s phospholipids, DHA, EPA, astaxanthinâ€â€all
can be readily inserted into cell membranes.
Krill oil has produced impressive benefits in clinical trials, superior when
compared against fish oil.
Superior to Fish Oil For Premenstrual Challenges
In a large proportion of women, premenstrual
problems affect life quality by negatively affecting mood and other mental
state and by generating pain and other physical problems. In a double blind
trial, krill oil was compared against fish oil for the relief of ten well
recognized premenstrual complaints.4 Seventy (70) women of childbearing age
consumed 2 grams of either a krill oil or a fish oil, daily for the first
month. Then for the next 2 months, they took the assigned supplements for just
eight days prior to menstruation and another 2 days subsequent. They filled in
detailed questionnaires and kept track of their daily analgesic (painkiller)
medication use.
After the first 45 days the women taking krill oil had significant
improvements in all 10 complaints, including irritability, depression, stress,
and “feelings of being overwhelmed.â€ï†4 The physical complaints
that improved included breast tenderness, joint pain, weight gain, abdominal
pain, swelling, and bloating. Those taking fish oil reported improvements in
just 2 physical complaintsâ€â€weight gain and abdominal pain. From day 45 to
day 90 all the krill oil benefits were sustained while for the fish oil group
only relief of swelling was added.
The superior benefits from krill oil also showed in the women’s lowered
reliance on painkillers.4 By day 90, those receiving krill oil were
able to reduce their daily consumption of ibuprofen or acetaminophen by more
than half. Those receiving fish oil reduced ibuprofen by 33 percent and
acetaminophen by 41 percent. The women taking krill oil also avoided the
unpleasant reflux regurgitation experienced by two-thirds of the women who
took the fish oil.
Superior Support for Cholesterol, Triglyceride and Blood Sugar Management
Blood lipid abnormalities including elevated
LDL cholesterol and total cholesterol, reduced HDL cholesterol, and high
triglycerides, are proven risk factors for cardiovascular disease5
and are also linked to premature memory decline.6 In a randomized
clinical trial, 120 men and women with hyperlipidemia (abnormally high total
cholesterol and triglyceride levels) received either krill oil, fish oil or a
placebo for 90 days.7 The krill oil dosages ranged from 1-3 grams
per day and were tailored to body mass index (BMI); the fish oil dosage was 3
grams per day. The trial went for 90 days.
Krill oil significantly lowered total and LDL cholesterol, and elevated HDL
cholesterol, at dosages of 1 gram and higher per day.7 At 2 and 3
grams per day, krill oil also significantly lowered triglycerides. Krill oil
at 1 gram per day and higher also significantly lowered fasting blood glucose.
The fish oil failed to lower total and LDL cholesterol, raised HDL cholesterol
only marginally (by 4 percent), and failed to lower triglycerides or blood
glucose. Krill oil’s superior cardiovascular benefits in this trial are
nicely complemented by its benefit against another major cardiovascular risk
factor CRP (C-reactive protein),8 as described in the next section.
Support for Joint Health and Lowering of CRP
In a double blind trial, 90 subjects with
severe joint complaints and/or cardiovascular problems were randomized to
receive either krill oil (300 mg per day) or a placebo.8 They were
assessed at baseline, then after 7, 14 and 30 days. They were allowed to use
only acetaminophen for pain. Already at day 7, krill oil significantly
improved joint pain (by 29 percent), stiffness (by 20 percent), and functional
impairment (by 30 percent). By day 30, pain was down by 38 percent in the
krill group, stiffness was 39 percent improved, and function was 36 percent
improved, versus no improvement in the placebo group. The subjects receiving
krill were able to lower their acetaminophen intake by 32 percent, while those
on placebo reduced theirs significantly less (6 percent).
Another finding from this trial was that krill oil significantly reduced CRP.8
This blood protein is a useful marker for inflammatory activity occurring
virtually anywhere in the body. Ongoing inflammation is a risk factor for poor
health, wherever it occurs, in the gums for example.9 Best measured
by an inexpensive test called “highly sensitive CRPÃ¢â‚¬ï† test (hsCRP),
elevated CRP is a strong predictor of future risk for cardiovascular or brain
“adverse events.â€ï†10 Assessing cardiovascular risk via CRP
testing is a useful complement to cholesterol testing, especially since
cholesterol assessment falls far short of predicting all cardiovascular risk.11
In this trial krill oil reduced CRP by 19 percent at day 7, compared to a 16
percent increase in the placebo group.8 The increase in the placebo
subjects likely was related to their being taken off their anti-inflammatory
medications (except for acetaminophen). At day 30 CRP was reduced by 31
percent in the krill group but was increased by 25 percent in the placebo
group. The ability to lower CRP is a valuable contribution of krill oil to
healthy immunity and cardiovascular function, and therefore to health overall.
Krill’s Vital Lipids Build Cell Membranes, Ensure Cell Functions
Every cell has a membrane system that performs
most of the necessary life processes.12 Membranes are thin,
interconnecting molecular sheets that define the cell’s outer border and
extend into the cell interior. The membrane’s foundation or matrix consists
mostly of phospholipids with fatty acids attached (DHA and EPA, for example).
Numerous catalytic proteins are inserted into this matrix, and these must be
free to move, which requires the matrix be semi-fluid. The omega-3
phospholipids of krill provide this natural fluidizing effect.
For humans as well as for krill, omega-3 phospholipids are natural cell
membrane fluidizers. They also drive metabolism: since fluidity facilitates
the membrane proteins, the higher the omega-3 phospholipid content in a
membrane the higher its metabolic activity.13 PhosphatidylCholine
(PC) is the most common phospholipid in all human cells,12 and
krill oil complex is an excellent dietary source of omega-3 PC carrying DHA
and EPA.
Antarctic Krill Oil Complex, A Dietary Supplement Breakthrough
Fish stocks worldwide are threatened with
depletion, due to unsustainable fishing practices.14 Krill stocks
are not. A visionary international cooperation begun in 1982 continues to
ensure that Antarctic krill harvesting remains sustainable. In that year the
CCAMLR, the Convention on the Conservation of Antarctic Marine Living
Resources, was founded as a multinational organization to exclusively set and
regulate “precautionaryÃ¢â‚¬ï† catch quotas for the krill and other Antarctic
fisheries.15
Real Krill comes from Antarctic krill fished using proprietary eco-harvesting
techniques. Developed in close cooperation with the World Wildlife Fund, these
advanced techniques virtually eliminate “by-catchÃ¢â‚¬ï† problems, combat
illegal fishing, and facilitate scientific documentation of the krill fishery.
The post-catch krill processing is also a major advance, using a nontoxic
solvent (ethanol) to help produce krill oil with the highest available levels
of omega-3s and phospholipids, free of environmental chemical contamination.
Fish oils are a popular dietary supplement category, yet they do not
predictably improve cholesterol management7 or lower CRP,16
nor do they consistently benefit mood management as seen in the premenstrual
trial.4 Krill oil provides a broader spectrum of benefits than does
fish oil, and at much lower daily intakes.
How to Use Real Krill
Each softgel capsule of this breakthrough
dietary supplement provides 350 mg of highest-grade Antarctic krill oil
complex. As maintenance intake, take 1 softgel daily with a small meal. To
support healthy mood management, take 2-3 softgels per day. To support healthy
blood lipid management and joint health, take 3 softgels per day. This
supplement is not vegetarian and may not be suitable for individuals with
seafood allergies.
Cell membranes are fundamental to life processes, and Real Krill is a cell
membrane supplement remarkable for its superior support of the brain,4
circulation,7 immune system,8 joints,8 heart,17
and liver,17,18 and for health and wellbeing overall.
Prepared for Doctor’s Best by Parris M. Kidd, PhD.
Does Not Contain: milk, egg, wheat, gluten, corn, soy, sugar, sweeteners, starch, salt, or preservatives.
- Hewitt RP, Watkins JL, Naganobu M, others. Setting a precautionary catch limit for Antarctic krill. Oceanography 2002;15:26-33.
- Kidd PM. Omega-3 DHA and EPA for cognition, behavior and mood: clinical findings and structural-functional synergies with cell membrane phospholipids. Altern Med Rev 2007;12:207-227.
- McNulty HP, Byun J, Lockwood SF, others. Differential effects of carotenoids on lipid peroxidation due to membrane interactions. Biochim Biophys Acta 2007;1768:167-174.
- Sampalis F, Bunea R, Pelland MF, others. Evaluation of the effects of Neptune Krill OilTM on the management of premenstrual syndrome and dysmenorrhea. Altern Med Rev 2003;8:171-179.
- Kumari U, Heese K. Cardiovascular dementia-a different perspective. Open Biochem J 2010;4:29-52.
- Raffaitin C, Gin H, Empana J-P, others. Metabolic syndrome and risk for incident Alzheimer’s disease or vascular dementia. Diabetes Care 2009;32:169-174.
- Bunea R, El Farrah K, Deutsch L. Evaluation of the effects of Neptune krill oil on the clinical course of hyperlipidemia. Altern Med Rev 2004;9:420-428.
- Deutsch L. Evaluation of the effects of Neptune krill oil on chronic inflammation and arthritic symptoms. J Am Coll Nutr 2007;26:39-48.
- Moutsopoulos NM, Madianos PN. Low-grade inflammation in chronic infectious diseases. Paradigm of periodontal infections. Ann NY Acad Sci 2006; 1088:251-264.
- Emerging Risk Factors Collaboration, Kaptoge S, Di Angelantonio E, others. C-reactive protein concentration and risk of coronary heart disease, stroke and mortality: an individual participant meta-analysis. Lancet 2010;375(9709):132-140.
- Ridker PM, Rifai N, Rose L, others. Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events. N Engl J Med 2002;347:1557-1565.
- Alberts B, Johnson A, Lewis J, et al. Molecular Biology of the Cell (Fourth Edition). New York: Garland Science; 2002.
- Hulbert A. Membrane fatty acids as pacemakers of animal metabolism. Lipids 2007;42:811-819.
- McMichael AJ, Butler CD. Fish, health, and sustainability. Am J Prev Med 2005;29:322-323.
- www.ccamlr.org (accessed May 30, 3010).
- Chan EJ, Cho L. What can we expect from omega-3 fatty acids? Cleveland Clinic J Med 2009;76:245-251.
- Batetta B, Griinari M, Carta G, others. Reduction of ectopic fat and susceptibility to inflammation in obese Zucker rats by dietary omega-3 fatty acids: Potential involvement of endocannabinoids. J Nutr 2009; 139:1495-1501.
- Tandy S, Chung R, Wat E, others. Dietary krill oil supplementation significantly reduces hepatic steatosis, glycemia and hypercholesterolemia in high-fat fed mice. J Agric Food Chem 2009;57:9339-9345.
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